| Amoxicillin trihydrate Chemical Properties | |
| Melting point | >200°C (dec.) |
| alpha | D20 +246° (c = 0.1) |
| refractive index | 302 ° (C=0.1, H2O) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Slightly soluble in water, very slightly soluble in ethanol (96 per cent), practically insoluble in fatty oils. It dissolves in dilute acids and dilute solutions of alkali hydroxides. |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in water at 3.4mg/ml. |
Amoxicillin trihydrate is a hydrate that is the trihydrate form of amoxicillin
Amoxicillin was synthesized by Beecham Research Laboratories in 1968. A hydroxyl group was introduced on the benzene ring of ampicillin. Amoxicillin shows about a twofold higher serum concentration than ampicillin when administered orally. Double-blind comparative studies with ampicillin showed that amoxicillin was as effective as ampicillin when administered at half the ampicillin dose.
