Ampicillin trihydrate

Ampicillin functions by killing the bacteria or preventing their growth. After penetrating Gram-positive and Gram-negative bacteria, it acts as an irreversible inhibitor of the enzyme transpeptidase needed by bacteria to make the cell wall, which results to the inhibition of cell wall synthesis and eventually leads to cell lysis.

Ampicillin is a synthetic penicillin. Natural penicillin has a narrow antibacterial spectrum. Ampicillin has a broad antibacterial spectrum. Ampicillin is slightly soluble in water, insoluble in chloroform, ethanol, ether or fixed oil; it dissolves in dilute acid solution or dilute alkali solution, but is unstable in water and strong acid and alkali solution. Therefore, the stability and drug solubility of veterinary oral preparations determine one of the key technical indicators of its efficacy. Therefore, in animal clinical practice, ampicillin preparations usually include soluble powders, injections, powder injections, tablets, etc. For poultry medication, soluble powders are the most economical and convenient commonly used dosage forms; for large animals such as cattle, sheep, and pigs, injections and powder injections are the most commonly used dosage forms. It is mostly used clinically for pneumonia. White diarrhea, urinary tract infection, pleuropneumonia. It is generally used in combination with gentamicin, streptomycin, and kanamycin for good efficacy.