| Florfenicol Chemical Properties | |
| Melting point | 153 °C |
| Boiling point | 618℃ |
| alpha | 26 +17.9° (DMF) |
| density | 1.451±0.06 g/cm3(Predicted) |
| RTECS | DB6034000 |
| Fp | >110°(230°F) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Soluble in ethanol to 25mM and in DMSO to 100mM |
| form | solid |
| pka | 10.73±0.46(Predicted) |
| color | White to Off-White |
Florfenicol, also known as fluorosulfamethoxazole, is a commonly used veterinary antibiotic with a broad antibacterial spectrum, strong antibacterial effect, and low minimum inhibitory concentration (MIC). The antibacterial effect is 15-20 times that of chloramphenicol and thiamphenicol. The drug concentration in the tissue can reach the peak 60 minutes after administration of the feed, which can quickly control the disease. It is highly safe, non-toxic, and has no residue. It has no potential risk of causing aplastic anemia and is suitable for large-scale farms. It is mainly used to treat bovine respiratory diseases caused by Pasteurella and Haemophilus. It has a good effect on bovine foot rot caused by Fusobacterium. It is also used for infectious diseases of pigs and chickens caused by sensitive bacteria and bacterial diseases of fish.
